If you’re ready for that, testosterone can be a powerful tool. Women with low testosterone (yes, women need it, too!) might also benefit from TRT under a doctor’s guidance. It’s also a solid pick if you’re wary of long-term hormone replacement or want something with fewer regulatory hoops. Sermorelin’s natural approach can help without overwhelming your system. It’s ideal for most people in their 30s or 40s who are starting to feel "off" but don’t have severe symptoms of low testosterone. Testosterone, on the other hand, is the hormone you probably already know about. Think of it like a gentle coach encouraging your pituitary gland to get back in the game. A study in Reumatologia showed that boosting HGH among those who were deficient could improve bone density and lower fracture risk (though, keep in mind, most adults aren’t deficient in growth hormone). Those two benefits together impact metabolism and overall energy levels and feelings of vitality. Other research has also shown a tie between growth hormone and better mental capacity, memory, and mood. Exactly how growth hormones could influence mood and brain function isn’t clearly understood. Paired with strength training, the HGH action that sermorelin triggers could lead to even better results in terms of muscle mass and strength. And this is important, because there’s solid evidence that we begin naturally losing muscle around age 30—at a decline of 3 to 5% of muscle mass per decade. In contrast with their prior work, AVF actually did negatively impact GHRP-2’s efficacy at increasing serum GH levels this time. The inclusion of older men in the study was significant because older men have lower levels of sex steroids at baseline compared to young men (44). In contrast, GHRP-2 induction of GH was unaffected by either factor and still induced a greater 2-fold increase in pulsatile GH secretion compared to GHRH. All 24 men were given 2 injections of depot leuprolide acetate three weeks apart, following which 13 men were given saline and 11 were given 200 mg testosterone enanthate weekly for 3 doses. These findings demonstrate that GHRP-2 is a potent stimulator of GH secretion in both eugonadal and hypogonadal men with a synergistic effect when co-administered with GHRH, from which sermorelin is derived. Invigor Medical offers a secure and knowledgeable source for obtaining sermorelin, complete with the support of medical professionals. Talk to your doctor about all of your health concerns to develop an action plan to decrease your risk. Many men seek an evaluation for low testosterone after experiencing erectile dysfunction. Low testosterone or andropause is a clinical diagnosis that requires a documented low testosterone level and symptoms consistent with low testosterone. The AACC recommends a baseline level of free estrogen because some testosterone will be converted to estrogen, and a baseline estrogen level can help determine this conversion rate.3 Measured outcomes included serum GH, IGF-1, IGFBP-3, and testosterone levels in addition to body weight, BMI, and waist-hip ratio. Consistent with this observation, in a later study examining GH-deficient rats, sermorelin therapy was shown to result in an increase in testosterone secretion (26). Simultaneously, sermorelin uniquely stimulated both FSH and LH release, implying a potential role in the treatment of hypogonadism via the stimulation of endogenous testosterone production. But how are they connected, and does sermorelin increase testosterone levels? Using sermorelin instead of recombinant human growth hormone allows your body’s feedback systems to continue to regulate growth hormone release. It stimulates the natural release of growth hormone from your pituitary gland.4 Like testosterone, human growth hormone levels decrease with age, and this decrease causes similar symptoms to low testosterone. Other medical conditions can cause changes in body composition, energy levels, and muscle mass. Because the benefits of restoring growth hormone align with the benefits of restoring testosterone, the two therapies are frequently used together. Sermorelin works with your body’s natural rhythms by stimulating the natural release of growth hormone. Sermorelin has no reported long-term side effects in human clinical trials. Testosterone therapy comes in different forms which include tablets, injections or even gels. Take charge of your health with the SynergenX patient app, powered by SynergenX - a free, game-changing tool available now in the Apple and Android app stores! In short, Sermorelin and TRT are known to work well together, and Sermorelin is often recommended to give TRT patients an added boost to muscle gains, vitality, and overall quality of life.
